〜2009年

著書（日本語、英語）

  1. H. Kikutani, S. Inui, R. Sato, E. L. Barsumian, H. Owaki, K. Yamasaki, T. Kaisho, N. Uchibayashi, R. R. Hardy, T. Hirano, S. Tsunasawa, F. Sakiyama, M. Suemura, and T. Kishimoto.　1987. Molecular cloning of the gene encoding a low-affinity FceR(CD23). In Leucocyte Typing III, Oxford Univ. Press., p423-426.
  2. S. Inui, T. Kaisho, E. A. Clark, B. Seed, H. Kikutani, and T. Kishimoto. 1989. Expression of intact and mutant CDw40 on murine lymphocytes (cytoplasmic portion is essential for signal transduction through CDw40). In Leucocyte Typing IV, Oxford Univ. Press., p93-95.
  3. 改正恒康　1997. Immunoglobulin E, Immunoglobulin switch region, membrane IgG1, membrane IgE. In ノックアウトマウスデータブック,　中山書店, p244-246, 316.
  4. 改正恒康. 2000. 免疫とサイトカイン.In 新臨床医のための分子医学シリーズ サイトカインと疾患, 羊土社.
  5. 改正恒康. 2000. CXCR5, BLC/BCA-1 In ケモカインハンドブック, 秀潤社.
  6. T. Kaisho and S. Akira. 2002. Toll-like receptors, in Infectious Disease: Innate Immunity (edited by R. A. B. Ezekowitz and J. A. Hoffman), p177-189 (Humana, Totowa, New Jersey).
  7. O. Takeuchi, T. Kaisho and S. Akira. 2003. Toll-like receptor: Specificity and signaling, in Immunobiology of Carbohydrates (edited by Simon. Y. C. Wong and Gemma Arsequell), p87-100 (Landes Bioscience, Georgetown, TX, USA or Eurekah.com, Austin, TX, USA).
  8. T. Kaisho and S. Akira. 2003. The induction of dendritic cell activation and maturation by Toll-like receptor signaling, in Toll Receptors (edited by Tina Rich) p1-15 (Landes Bioscience, Georgetown, TX, USA or Eurekah.com, Austin, TX, USA)
  9. 改正恒康. 2003. 自然免疫とToll様受容体. In 免疫学最新イラストレイテッド. 羊土社、p19-34.
  10. T. Kaisho. 2005. Characteristics of nucleic acid TLR ligands. The Innate Immune System: Strategies for Disease Control (International Congress Series 1285). P34-41.
  11. T. Kaisho and S. Akira. 2007. Principles of innate immunity, in Fourth Edition Rheumatology vol.1 (edited by Marc C. Hochberg, Alan J. Silman, Josef S. Smolen, Michael E. Weinblatt. Michael H. Weisman). P143-150. (MOSBY , ELSEVIER, 1600 John F. Kennedy Boulevard, Suite 1800, Philadelphia, PA 19103-2899, USA)
  12. T. Kaisho, T. Sugiyama and K. Hoshino. 2008. Characteristics of dendritic cell responses to nucleic acids, in Nucleic Acids in Innate Immunity (edited by Ken J. Ishii and Shizuo Akira), p43-58 (CRC Press, USA)
  13. 改正恒康. 2009. 自然免疫とToll様受容体. In 改訂第2版 免疫学最新イラストレイテッド. 羊土社、p25-39.
  14. T. Kaisho and S. Akira. 2011. Principles of innate immunity, in Fifth Edition Rheumatology vol.1 (edited by Marc C. Hochberg, Alan J. Silman, Josef S. Smolen, Michael E. Weinblatt. Michael H. Weisman). P141-151. (MOSBY , ELSEVIER, 1600 John F. Kennedy Boulevard, Suite 1800, Philadelphia, PA 19103-2899, USA)

Review

  1. T. Matsuda, T. Nakajima, T. Kaisho, K. Nakajima, and T. Hirano. 1994. Interleukin 6 receptor and signal transduction. Advances in Cell and Molecular Biology of Membranes and Organelles. 3: 65-92.
  2. T. Kaisho and S. Akira. 2000. Critical roles of Toll-like receptors in host defense. Critical Reviews in Immunology. 20:393-405.
  3. S. Akira, K. Hoshino and T. Kaisho. 2000. The role of Toll-like receptors and MyD88 in innate immune responses. Journal of Endotoxin Research 6;383-387.
  4. T. Kaisho and S. Akira. 2001. Dendritic-cell function in Toll-like receptor- and MyD88-knockout mice. Trends Immunol. 22:78-83.
  5. S. Akira, K. Takeda and T. Kaisho. 2001. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2: 675-680.
  6. T. Kaisho and S. Akira. 2001. Toll-like receptors and their signaling mechanism in innate immunity. Acta Odontolo. Scand. 59: 124-130.
  7. T. Kaisho and S. Akira. 2001. Bug detectors. Nature 414: 701-703.
  8. T. Kaisho and S. Akira. 2002. Toll-like receptors as adjuvant receptors. Biochimica et Biophysica Acta 1589:1-13.
  9. T. Takeda, T. Kaisho, and S. Akira. 2003. Toll-like receptors. Ann Rev Immunol 21: 335-376.
  10. T. Kaisho, and S. Akira. 2003. Regulation of dendritic cell function through Toll-like receptors. Curr. Mol. Med. 3: 373-385.（Corrected version, 759-771）
  11. T. Kaisho, S. Akira. 2004. Pleiotropic function of Toll-like receptors. Microbes Infect. 6:1388-1394.
  12. T. Kaisho, S. Akira. Toll-like receptors. Encyclopedia of Life Sciences, published on line. 23 September, 2005.
  13. T. Kaisho, S. Akira. 2006. TLR function and signaling. J. Allergy Clin. Immunol. 117:979-987.
  14. T. Kaisho. 2008. Type I interferon production by nucleic acid-stimulated dendritic cells. Front. Biosci. 13:6034-6042.
  15. T. Kaisho, T. Tanaka. 2008. Turning NF-B and IRFs on and off in DC. Trends Immunol. 29:329-336.
  16. K. Hoshino, T. Kaisho. 2008. Nucleic acid sensing Toll-like receptors in dendritic cells. Curr. Opin. Immunol. 20:408-413.
  17. T. Kaisho, H. Wagner. 2008. Host-pathogen interactions (Editorial). Curr. Opin. Immunol. 20:369-370.
  18. T. Kaisho, K. Takeda. 2009. The study of innate immunity in Japan: a historical perspective. Int. Immunol. 21:313-316.
  19. T. Kaisho. 2010. Molecular mechanisms for plasmacytoid dendritic cell function and development. Vaccine 28:8046-8047. 20.

原著

  1. H. Kikutani, S. Inui, R. Sato, E. L. Barsumian, H. Owaki, K. Yamasaki, T. Kaisho, N. Uchibayashi, R. R. Hardy, T. Hirano, S. Tsunasawa, F. Sakiyama, M. Suemura, and T. Kishimoto. 1986. Molecular structure of human lymphocyte receptor for immunoglobulin E. Cell 47:657-665.
  2. 改正恒康. 1990. ヒトBリンパ球特異抗原CD40のシグナル伝達に必須な細胞質内領域の同定. 大阪大学医学雑誌42:63-75.
  3. S. Inui, T. Kaisho, H. Kikutani, I. Stamenkoric, B. Seed, E. A. Clark, and T. Kishimoto. 1990. Identification of the intracytoplasmic region essential for signal transduction through a B cell activation molecule, CD40. Eur. J. Immunol. 20:1747-1753.
  4. T. Kaisho, T. Nagasawa, T. Kishimoto and H. Kikutani. 1992. A stromal cell-specific monoclonal antibody augments the stromal cell-dependent B lymphopoiesis. J. Immunol. 148:989-995.
  5. T. Kaisho, K. Oritani, J. Ishikawa, M. Tanabe, O. Muraoka, T. Ochi, and T. Hirano. 1992. Human bone marrow stromal cell lines from myeloma and rheumatoid arthritis that can support murine preB cell growth. J. Immunol. 149:4088-4095.
  6. K. Oritani, T. Kaisho, K. Nakajima and T. Hirano. 1992. Retinoic acid inhibits interleukin 6-induced macrophage differentiation and apoptosis in a murine hematopoietic cell line, Y6. Blood　80:2298-2305.
  7. T. Matsuda, T. Nakajima, T. Kaisho, K. Nakajima, and T. Hirano. 1994. Interleukin 6 receptor and signal transduction. Advances in Cell and Molecular Biology of Membranes and Organelles. 3: 65-92.
  8. M. A. Brach, H.-J. Grub, T. Kaisho, Y. Asano, T. Hirano, and F. Herrmann. 1993. Ionizing radiation induces expression of Interleukin 6 by human fibroblasts involving activation of Nuclear Factor-kB. J. Biol. Chem. 268: 8466-8472.
  9. O. Muraoka, T. Kaisho, M. Tanabe, and T. Hirano. 1993. Transcriptional activation of the interleukin 6 gene by HTLV-1 p40tax through an NF-kappaB-like binding site. Immunol. Lett. 37:159-165.
  10. T. Nagasawa, T. Kaisho, T. Kishimoto, and H. Kikutani. 1994. Generation and characterization of a monoclonal antibody that inhibits stromal cell-dependent B lymphopoiesis. J. Immunol. 152:2788-2797.
  11. T. Kaisho, J. Ishikawa, K. Oritani, J. Inazawa, H. Tomizawa, O. Muraoka, T. Ochi, and T. Hirano. 1994. BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth. Proc. Natl. Acad. Sci. USA 91:5325-5329.
  12. M. Itoh, K. Ishihara, H. Tomizawa, H. Tanaka, Y. Kobune, J. Ishikawa, T. Kaisho and T. Hirano. 1994. Molecular cloning of murine BST-1 having homology with CD38 and Aplysia ADP-ribosyl cyclase. Biochem. Biophys. Res. Commun. 203:1309-1317.
  13. Y. Hirata, N. Kimura, K. Sato, Y. Ohsugi, S. Takasawa, H. Okamoto, J. Ishikawa, T. Kaisho, K. Ishihara and T. Hirano. 1994. ADP ribosyl cyclase activity of a novel bone marrow stromal cell surface molecule, BST-1. FEBS Letters 356: 244-248.
  14. J. Ishikawa, T. Kaisho, H. Tomizawa, B. O. Lee, Y. Kobune, J. Inazawa, K. Oritani, M. Ito, T. Ochi, K. Ishihara, and T. Hirano. 1995. Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, may be involved in pre-B-cell growth. Genomics 26:527-534. The first two authors equally contributed to this work.
  15. E. A. Clark, K. H. Grabstein, A. M. Gown, M. Skelly, T. Kaisho, T. Hirano and G. L. Shu. 1995. Activation of B lymphocyte maturation by a human follicular dendritic cell line, FDC-1. J. Immunol. 155:545-555.
  16. J. Sanceau, T. Kaisho, T. Hirano, and J. Wietzerbin. 1995. Triggering of the human interleukin-6 gene by interferon-g and tumor necrosis factor-a in monocytic cells involves cooperation between IRF-1, NF-B, and Sp1 transcription factors. J. Biol. Chem. 270:27920-27931.
  17. Y. Kajimoto, J. Miyagawa, K. Ishihara, Y. Okuyama, Y. Fujitani, M. Itoh, H. Yoshida, T. Kaisho, T. Matsuoka, H. Watada, T. Hanafusa, Y. Yamasaki, T. Kamada, Y. Matsuzawa, and T. Hirano. 1996. Pancreatic islet cells express BST-1, a CD38-like surface molecule having ADP-ribosyl cyclase activity. Biochem. Biophys. Res. Commun. 219: 941-946.
  18. B. O. Lee, K. Ishihara, K. Denno, Y. Kobune, M. Itoh, O. Muraoka, T. Kaisho, T. Sasaki, T. Ochi, and T. Hirano. 1996. Elevated levels of the soluble form of bone marrow stromal cell antigen 1 in the sera of patients with severe rheumatoid arthritis. Arthritis Rheum. 39:629-637.
  19. T. Kaisho, F. Schwenk, K. Rajewsky. 1997. The role of 1 heavy-chain membrane expression and cytoplasmic tail in IgG1 responses. Science 276:412-415.
  20. H. Akaishi, K. Takeda, T. Kaisho, R. Shineha, S. Satomi, J. Takeda, and S. Akira. 1998. Defective IL-2-mediated IL2 receptor a chain expression in Stat3-deficient T lymphocytes. Int. Immunol. 10:1747-1751.
  21. K. Takeda, T. Kaisho, N. Yoshida, J. Takeda, T. Kishimoto, and S. Akira. 1998. Stat3 Activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific stat3-deficient mice. J. Immunol. 161:4652-4660.
  22. K. Takeda, B. E. Clausen, T. Kaisho, T. Tsujimura, N. Terada, I. Foerster, and S. Akira. 1999. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity 10:39-49.
  23. T. Tsujimura, K. Hashimoto, H. Kitayama, H. Ikeda, H. Sugahara, I. Matsumura, T. Kaisho, N. Terada, Y. Kitamura, and Y. Kanakura. 1999. Acitivating mutation in the catalytic domain of c-kit elicits hematopoietic transformation by receptor self-association not at the ligand-induced dimerization site. Blood 93:1319-1329.
  24. Y. Sakao, K. Takeda, H. Tsutsui, T. Kaisho, F. Nomura, H. Okamura, K. Nakanishi, and S. Akira. 1999. IL18-deficient mice are resistnant to endotoxin-induced liver injury but highly susceptible to endotoxin shock. Int. Immunol. 11:471-480.
  25. M. Matsumoto, T. Tanaka, T. Kaisho, H. Sanjo, N. G. Copeland, D. J. Gilbert, N. A. Jenkins, and S. Akira. 1999. A novel LPS-inducible C-type lectin is a transcriptional target of NF-IL6 in macrophages. J. Immunol. 163:5039-5048.
  26. T. Kaisho, H. Tsutsui, T. Tanaka, T. Tsujimura, K. Takeda, T. Kawai, N. Yoshida, K. Nakanishi, and S. Akira. 1999. Impairment of natural killer cytotoxic activity and interferon- production in C/EBP-deficient mice. J. Exp. Med. 190:1573-1581.
  27. A. Hashimoto, K. Takeda, M. Inaba, M. Sekimata, T. Kaisho, S. Ikehara, Y. Homma, S. Akira, and T. Kurosaki. 2000. Essential role of phospholipase C-2 in B cell development and function. J. Immunol. 165:1738-1742.
  28. H. Hemmi, O. Takeuchi, T. Kawai, T. Kaisho, S. Sato, H. Sanjo, K. Hoshino, H. Wagner, K. Takeda, and S. Akira. 2000. A Toll-like receptor recognizes bacterial DNA. Nature 408:740-745.
  29. T. Kaisho, K. Takeda, T. Tsujimura, T. Kawai, F. Nomura, N. Terada, and S. Akira. 2001. IB kinase is essential for mature B cell development and function. J. Exp. Med. 193:417-426.
  30. A. Matsushima, T. Kaisho, P.D. Rennert, H. Nakano, K. Kurosawa, D. Uchida, K. Takeda, S. Akira, and M. Matsumoto. 2001. Essential role of nuclear factor (NF)-B-inducing kinase and inhibitor of B (IB) kinase in NF-B activation through lymphotoxin  receptor, but not through Tumor Necrosis Factor Receptor I. J. Exp. Med. 193:631-636.
  31. T. Kaisho, O. Takeuchi, T. Kawai, K. Hoshino, and S. Akira. 2001. Endotoxin-induced maturation of MyD88-deficient dendritic cells. J. Immunol. 166:5688-5694.
  32. A. Suzuki, M. Tsukio-Yamaguchi, T. Ohteki, T. Sasaki, T. Kaisho, Y. Kimura, R. Yoshida, A. Wakeham, T. Higuchi, M. Fukumoto, T. Tsubata, P. S. Ohashi, S. Koyasu, J. M. Penninger, T. Nakano, and T. W. Mak. 2001. T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance. Immunity 14:523-534.
  33. H. Hemmi, T. Kaisho, O. Takeuchi, S. Sato, H. Sanjo, K. Hoshino, T. Horiuchi, H. Tomizawa, K. Takeda, and S. Akira. 2002. Small anti-viral compounds activate immune cells via the TLR7 MyD88- dependent signaling pathway. Nat. Immunol. 3:196-200.
  34. T. Kaisho, K. Hoshino, T. Iwabe, O. Takeuchi, T. Yasui, and S. Akira. 2002. Endotoxin can induce MyD88-deficient dendritic cells to support Th2 cell differentiation. Int. Immunol. 14:695-700.
  35. T. Ito, R. Amakawa, T. Kaisho, H. Hemmi, K. Tajima, K. Uehira, Y. Ozaki, H. Tomizawa, S. Akira, S. Fukuhara. 2002. Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets. J Exp Med. 195:1507-1512.
  36. T. Iwasaki, K. Yamashita, T. Tsujimura, S. Kashiwamura, H. Tsutsui, T. Kaisho, A. Sugihara, N. Yamada, M. Mukai, T. Yoneda, H. Okamura, H. Akedo, N. Terada. 2002. Interleukin-18 inhibits osteolytic bone metastasis by human lung cancer cells possibly through suppression of osteoclastic bone-resorption in nude mice. J Immunother. Suppl 1:S52-60.
  37. K. Hoshino, T. Kaisho, T. Iwabe, O. Takeuchi, S. Akira. 2002. Differential involvement of IFN- in Toll-like receptor-stimulated dendritic cell activation. Int. Immunol. 14: 1225-1231.
  38. A. D. Edwards, S. P. Manickasingham, R. Spoerri, S. S. Diebold, O. Shulz, A. Sher, T. Kaisho, S. Akira, and C. Reis e Sousa. 2002. Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering. J. Immunol. 169:3652-3660.
  39. M. Yamamoto, S. Sato, H. Hemmi, H. Sanjo, S. Uematsu, T. Kaisho, K. Hoshino, O. Takeuchi, M. Kobayashi, T. Fujita, K. Takeda, and S. Akira. 2002.　Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature 420:324-329.
  40. H. Hemmi, T. Kaisho, K. Takeda, and S. Akira. 2003. The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets. J. Immunol. 170: 3059-3064.
  41. A. Suzuki, T. Kaisho, M. Ohishi, M. Tsukio-Yamaguchi, T. Tsubata, P. A. Koni, T. Sasaki, T. W. Mak, and T. Nakano. 2003. Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination. J. Exp. Med. 197: 657-667.
  42. A. D. Edwards, S. S. Diebold, E. M. Slack, H. Tomizawa, H. Hemmi, T. Kaisho, S. Akira, and C. Reis e Sousa. 2003. Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8alpha+ DC correlates with unresponsiveness to imidazoquinolines. Eur. J. Immunol. 33: 827-833.
  43. M. Yamamoto, S. Sato, H. Hemmi, K. Hoshino, T. Kaisho, H. Sanjo, O. Takeuchi, M. Sugiyama, M. Okabe, K. Takeda, and S. Akira. 2003. Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway. Science 301: 640-643.
  44. Y. Ebisuno, T. Tanaka, N. Kanemitsu, H. Kanda, K. Yamaguchi, T. Kaisho, S. Akira, and M. Miyasaka. 2003. Cutting Edge: The B Cell chemokine CXC chemokine ligand 13/B Lymphocyte chemoattractant is expressed in the high endothelial venules of lymph nodes and Peyer's patches and affects B Cell trafficking across high endothelial venules. J. Immunol. 171: 1642-1646.
  45. K. Honda, S. Sakaguchi, C. Nakajima, A. Watanabe, H. Yanai, M. Matsumoto, T. Ohteki, T. Kaisho, A. Takaoka, S. Akira, T. Seya, and T. Taniguchi. 2003. Selective contribution of IFN- signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection. Proc. Natl. Acad. Sci. U S A 100:10872-10877.
  46. M. Yamamoto, S. Sato, H. Hemmi, S. Uematsu, K. Hoshino, T. Kaisho, O. Takeuchi, K. Takeda, S. Akira. 2003. TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway. Nat. Immunol. 4:1144-1150.
  47. H. Kuwata, Y. Watanabe, H. Miyoshi, M. Yamamoto, T. Kaisho, K. Takeda, S. Akira. 2003. IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF- production in macrophages. Blood 102:4123-4129.
  48. M. Yamada, K. Oritani, T. Kaisho, J. Ishikawa, H. Yoshida, I. Takahashi, S. Kawamoto, N. Ishida, H. Ujiie, H. Masaie, M. Botto, Y. Tomiyama, Y. Matsuzawa. 2004. Complement C1q regulates LPS-induced cytokine production in bone marrow-derived dendritic cells. Eur. J. Immunol. 34:221-230.
  49. S. S. Diebold, T. Kaisho, H. Hemmi, S. Akira, C. Reis e Sousa. 2004. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303:1529-1531.
  50. H. Hemmi, O. Takeuchi, S. Sato, M. Yamamoto, T. Kaisho, H. Sanjo, T. Kawai, K. Hoshino, K. Takeda, S. Akira. 2004. The roles of two IB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection. J. Exp. Med. 199:1641-1650.
  51. M. Yamamoto, S. Yamazaki, S. Uematsu, S. Sato, H. Hemmi, K. Hoshino, T. Kaisho, H. Kuwata, O. Takeuchi, K. Takeshige, T. Saitoh, S. Yamaoka, N. Yamamoto, S. Yamamoto, T. Muta, K. Takeda, S. Akira. 2004. Regulation of Toll/IL-1-receptormediated gene expression by the inducible nuclear protein IB. Nature 430:218-222.
  52. N. Okazaki, R. F. Kikuno, R. Ohara, S. Inamoto, H. Koseki, S. Hiraoka, Y. Saga, S. Seino, M. Nishimura, T. Kaisho, K. Hoshino, H. Kitamura, T. Nagase, O. Ohara, H. Koga. 2004. Prediction of the Coding Sequences of Mouse Homologues of KIAA Gene: IV. The Complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs indentified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Research 11:205-218.
  53. T. Sugiyama, M. Gursel, F. Takeshita, C. Coban, J. Conover, T. Kaisho, S. Akira, D. M. Klinman, K. J. Ishii. 2005. CpG RNA: Identification of Novel Single-Stranded RNA That Stimulates Human CD14+CD11c+ Monocytes. J. Immunol. 174:2273-2279.
  54. Y. Nagai, T. Kobayashi, Y. Motoi, K. Ishiguro, A. Akashi, S. Saitoh, Y. Kusumoto, T. Kaisho, S. Akira, M. Matsumoto, K. Takatsu, K. Miyake. 2005. The Radioprotective　105/MD-1 Complex Links TLR2 and TLR4/MD-2 in Antibody Response to Microbial Membranes. J. Immunol. 174:7043-7049.
  55. N. Kanemitsu, Y. Ebisuno, T. Tanaka, K. Otani, H. Hayasaka, T. Kaisho, S. Akira, K. Katagiri, T. Kinashi, N. Fujita, T. Tsuruno, M. Miyasaka. 2005. CXCL13 is an arrest chemokine for B cells in high endothelial venules. Blood 106: 2613-2618.
  56. D. Kinoshita, F. Hirota, T. Kaisho, M. Kasai, K. Izumi, Y. Bando, Y. Mouri, A. Matsushima, S. Niki, H. Han, K. Oshikawa, N. Kuroda, M. Maegawa, M. Irahara, K. Takeda, S. Akira, M. Matsumoto. 2006. Essential role of IB kinasein thymic organogenesis required for the establishment of self-tolerance. J. Immunol. 176: 3995-4002.
  57. K. Hoshino, T. Sugiyama, M. Matsumoto, T. Tanaka, M. Saito, H. Hemmi, O. Ohara, S. Akira, T. Kaisho. 2006. IB kinase- is critical for interferon- production induced by Toll-like receptors 7 and 9. Nature 440: 949-953.
  58. M. Saito, K. Hoshino, T. Sugiyama, T. Tanaka, R. Tsuboi, T. Kaisho. 2006. Gene expression profiles of mouse dendritic cell subsets. J. Tokyo Med.Univ. 64(3):294-304.
  59. H. Kitamura, H. Morikawa, H. Kamon, M. Iguchi, S. Hojyo, T. Fukada, S. Yamashita, T. Kaisho, S. Akira, M. Murakami and T. Hirano. 2006. Toll-like receptor-mediated regulation of zinc homeostasis influences dendritic cell function. Nat. Immunol. 7: 971-977.
  60. H. Kamon, T. Kawabe, H. Kitamura, J. Lee, D. Kamimura, T. Kaisho, S. Akira, A. Iwamatsu, H. Koga, M. Murakami, T. Hirano. 2006. TRIF-GEFH1-RhoB pathway is involved in MHCII expression on dendritic cells that is critical for CD4 T-cell activation. EMBO J. 25: 4108-4119.
  61. S. Fukuyama, T. Nagatake, D.Y. Kim, K. Takamura, E. J. Park, T. Kaisho, N. Tanaka, Y. Kurono, H. Kiyono. 2006. Uniqueness of lymphoid chemokine requirement for the initiation and maturation of nasopharynx-associated lymphoid tissue organogenesis. J. Immunol. 177: 4276-4280.
  62. S. A. Ha, M. Tsuji, K. Suzuki, B. Meek, N. Yasuda, T. Kaisho and S. Fagarasan. 2006. Regulation of B1 cell migration by signals through Toll-like receptors. J. Exp. Med. 203:2541-2550.
  63. R. Samarasinghe, P. Tailor, T. Tamura, T. Kaisho, S. Akira, K. Ozato. 2006. Induction of an anti-inflammatory cytokine, IL-10, in dendritic cellsafter toll-like receptor signaling. J. Interferon Cytokine Res. 26(12):893-900.
  64. T. Tanaka, M. J. Grusby and T. Kaisho. 2007. PDLIM2-mediated termination of transcription factor NF-B activation by intranuclear sequestration and degradation of the p65 subunit. Nat. Immunol. 8(6):584-591.
  65. S. K. Pathak, S. Basu, K. K. Basu, A. Banerjee, S. Pathak, A. Bhattacharyya, T. Kaisho, M. Kundu and J. Basu. 2007. Direct extracellular interaction between the early secreted antigen ESAT-6 of mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophsages. Nat. Immunol. 8(6):610-618.
  66. S. Uematsu, T. Kaisho, T. Tanaka, M. Matsumoto, M. Yamakami, H. Omori, M. Yamamoto, T. Yoshimori and S. Akira. 2007. The C/EBP Isoform 24-kDa LAP is responsible for NF-IL-6-mediated gene induction in activated macrophsges, but is not essential for intracellular bacteria killing. J. Immunol. 179: 5378-5386.
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    76. 総説（日本語）

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